Furans Conjugated with Bulky Aromatic Systems: One-Pot Synthesis from Ketones and Acetylene.

نویسندگان

  • Elena Yu Schmidt
  • Ivan A Bidusenko
  • Natalia A Cherimichkina
  • Igor A Ushakov
  • Tatyana N Borodina
  • Vladimir I Smirnov
  • Boris A Trofimov
چکیده

Ketones with bulky aromatic, heteroaromatic and ferrocene substituents react with acetylene in the presence of a KOH/DMSO super-base suspension (90 °C, 15 min) to give polysubstituted furans in up to 86 % isolated yields in a one-pot fashion. This assembly of the furan scaffold involves a domino sequence in which one molecule of ketone reacts with two molecules of acetylene.

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عنوان ژورنال:
  • Chemistry

دوره 21 45  شماره 

صفحات  -

تاریخ انتشار 2015