Furans Conjugated with Bulky Aromatic Systems: One-Pot Synthesis from Ketones and Acetylene.
نویسندگان
چکیده
Ketones with bulky aromatic, heteroaromatic and ferrocene substituents react with acetylene in the presence of a KOH/DMSO super-base suspension (90 °C, 15 min) to give polysubstituted furans in up to 86 % isolated yields in a one-pot fashion. This assembly of the furan scaffold involves a domino sequence in which one molecule of ketone reacts with two molecules of acetylene.
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ورودعنوان ژورنال:
- Chemistry
دوره 21 45 شماره
صفحات -
تاریخ انتشار 2015